Chromium's Hidden Role in Insulin Resistance, Metabolic Syndrome, and Diabetes

Abstract

In this study, we developed a spectrophotometric method to explore the association of nutrient composition, particularly of chromium, and insulin resistance. Forty volunteers were used for tissue concentrations by using the Oligo-Check spectrophotometer to determine chromium, zinc, and selenium measurements. Subjects were divided into low chromium (n=18) and normal chromium level (n=22) groups. Serum insulin and fasting blood glucose were determined by Roche Cobas systems, and HOMA-IR was calculated according to the formula. Findings showed that insulin resistance was significantly higher in the low chromium group, concluding that; "depleted chromium leads to insulin resistance., The implications of the study emphasize the need of watchfulness and regulation of chromium in patients with insulin resistance.

Bullet points:

• Spectrophotometric Analysis: Chromium, zinc, and selenium levels were measured in 40 volunteers using the Oligo-Check spectrophotometer.


• Group Comparison: Participants were divided into low-chromium (n = 18) and normal-chromium (n = 22) groups; insulin and fasting glucose were analyzed using Roche Cobas systems.


• Key Finding: The low-chromium group showed significantly higher HOMA-IR values, indicating that reduced chromium levels contribute to insulin resistance.